Several studies in the past have revealed that cannabis interacts with the receptors in the endocrine system. Not only this but the cannabinoids such as CBG, THC, and CBD have a significant impact on the hormones inside our body. In particular, hormones related to sleep, stress, energy, sexual activity, etc. Does this also mean that the endocannabinoid system and cannabinoids can also help restore hormonal imbalance? Read on to find out.
Hormones regulate many aspects of our physiology. For instance, mood, behavior, sleep, growth, etc. Even our body’s capacity to react to different elements depends on the hormones. And these compounds or to be precise hormones are produced by the endocrine system.
If you ever paid enough attention to the biology lessons taught in class, you might be able to recollect that the endocrine system is present in glands such as the thyroid, pineal, pituitary, and pancreas. The hormones produced by these glands regulate specific functions. For example, cortisol is a hormone that manages stress and melatonin regulates the sleep and wake cycle. Overall, hormones play a major role in controlling various functions inside our body.
Interestingly, our endocannabinoid system (ECS) activates receptors present inside the endocrine system. As a result of which, CBD can also activate endocrine receptors both inside the brain and body. While studies show that the ECS regulates the proliferation of endocrine cancer cells causing antitumor effects, other studies reveal it also limits the growth of cancer cells in oncologic diseases.
This also means that the relationship between the cannabinoids and hormones may be therapeutic in nature. In other words, cannabinoids can alleviate the symptoms of certain medical conditions. However, one of the challenges that the cannabis and medical community face is the lack of concrete evidence and in-depth research.
Excessive or low production of metabolic hormones can cause heart disease through reduced production of insulin. Diabetes and heart diseases are one of the best examples of damage caused to our body when insulin levels reduce drastically. While these damages can prove fatal, it’s quite evident that insulin balances our metabolism. Not only this but insulin turns the body sugar into energy and helps in the process of nutrition absorption. So, any imbalance in the production can lead to a bad effect on the body.
However, the main question is whether CBD can help restore that imbalance or not? According to a study, CBD has a significant impact on insulin production and pancreatic function. In simple words, CBD can influence sugar levels. Given that the ECS regulates the functioning of endocrine receptors, it’s quite possible that CBD therapy might help maintain healthy levels of insulin.
Sexual hormones are controlled by the pituitary gland and influenced by the hypothalamus. According to scientific research, it appears that cannabinoids also affect hypothalamic-pituitary-gonadal-axis. Here is a study that shows an evident connection between ECS and female hormones. This study shows that the ECS controls the mechanism of the menstrual cycle.
Unfortunately, not all cannabinoids work effectively in the case of gonadal hormones. In fact, another study showed that exposure to CBD can lead to a certain degree of impairment. Overall, the role of cannabis in the case of sexual hormones requires in-depth study and clinical research.
Yes, we are fully aware of the fact that CBD is often used for its relaxing effects. Moreover, medical conditions associated with sleep disorders are often treated with the help of medical cannabis. In fact, people renew MMJ card or get a cannabis recommendation to continue using medical marijuana for sleep-related problems. CBD may also stimulate the production of melatonin to improve sleep patterns.
All in all, CBD consumption can help increase the production of both cortisol and melatonin. Thus, improving the sleep cycle and causing the brain to produce cortisol. Which, in turn, alleviates the symptoms related to stress, anxiety, and even depression.
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